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Software - Open Source: Telometric Synopsis: Telometric is a software package that enables users to assess the sizes and distribution of telomeric fragments represented in autoradiograph images of agarose gels. The hybridization from multiple matching telomeric probes is corrected for and simple statistics and plots are generated for each selected lane. Telometric is available as an NIH Image macro or as a stand-alone Java application. The source code is released under the GNU general public license (GPL). Downloads Telometric Telometric-1.2: Java version (ftp link - recommended) Telometric-1.2: Java version (http link) Telometric-1.2 source code Telometric-1.0: NIH Image macro Documentation: Telometric User's Guides Telometric-1.2 (.pdf) Telometric-1.0 (.ps or .pdf) Notes on Telometric 1.2: Telometric 1.2 requires the following: Java 2 Runtime Environment Java Advanced Imaging JRE Install Telometric 1.2 has been tested under Linux, Windows 98, Windows NT, Windows 2000, and Windows XP. To invoke Telometric 1.2 from the command line, enter the following: java -jar telometric-1.2.jar Reference: 'Telometric: a tool providing simplified, reproducible measurements of telomeric DNA from constant field agarose gels', Grant J.D., Broccoli D., Muquit M., Manion F.J., Tisdall J., Ochs M.F., BioTechniques 31:1314-1318. Contact Information: Biostatistics and Bioinformatics Facility Fox Chase Cancer Center Philadelphia, PA